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Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b

Cholesterol is essential for cell physiology. Transport of the “accessible” pool of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) by ER‐localized GRAMD1 proteins (GRAMD1a/1b/1c) contributes to cholesterol homeostasis. However, how cells detect accessible cholesterol wit...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Ercan, Bilge, Naito, Tomoki, Koh, Dylan Hong Zheng, Dharmawan, Dennis, Saheki, Yasunori
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957428/
https://ncbi.nlm.nih.gov/pubmed/33604931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106524
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