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Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b

Cholesterol is essential for cell physiology. Transport of the “accessible” pool of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) by ER‐localized GRAMD1 proteins (GRAMD1a/1b/1c) contributes to cholesterol homeostasis. However, how cells detect accessible cholesterol wit...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Ercan, Bilge, Naito, Tomoki, Koh, Dylan Hong Zheng, Dharmawan, Dennis, Saheki, Yasunori
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957428/
https://ncbi.nlm.nih.gov/pubmed/33604931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106524
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