Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization

In many animal models, primordial germ cell (PGC) development depends on maternally deposited germ plasm, which prevents somatic cell fate. Here, we show that PGCs respond to regulatory information from the germ plasm in two distinct phases using two distinct mechanisms in zebrafish. We demonstrate...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Dev Cell
Egile Nagusiak: D’Orazio, Fabio M., Balwierz, Piotr J., González, Ada Jimenez, Guo, Yixuan, Hernández-Rodríguez, Benjamín, Wheatley, Lucy, Jasiulewicz, Aleksandra, Hadzhiev, Yavor, Vaquerizas, Juan M., Cairns, Bradley, Lenhard, Boris, Müller, Ferenc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957325/
https://ncbi.nlm.nih.gov/pubmed/33651978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.02.007
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