Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization

In many animal models, primordial germ cell (PGC) development depends on maternally deposited germ plasm, which prevents somatic cell fate. Here, we show that PGCs respond to regulatory information from the germ plasm in two distinct phases using two distinct mechanisms in zebrafish. We demonstrate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Dev Cell
मुख्य लेखकों: D’Orazio, Fabio M., Balwierz, Piotr J., González, Ada Jimenez, Guo, Yixuan, Hernández-Rodríguez, Benjamín, Wheatley, Lucy, Jasiulewicz, Aleksandra, Hadzhiev, Yavor, Vaquerizas, Juan M., Cairns, Bradley, Lenhard, Boris, Müller, Ferenc
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cell Press 2021
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957325/
https://ncbi.nlm.nih.gov/pubmed/33651978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.02.007
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