Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A

Microfluidic technology enables recapitulation of organ-level physiology to answer pertinent questions regarding biological systems that otherwise would remain unanswered. We have previously reported on the development of a novel product consisting of human placental cells (PLC) engineered to overex...

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Detalles Bibliográficos
Publicado en:Front Bioeng Biotechnol
Autores principales: Trevisan, Brady, Morsi, Alshaimaa, Aleman, Julio, Rodriguez, Martin, Shields, Jordan, Meares, Diane, Farland, Andrew M., Doering, Christopher B., Spencer, H. Trent, Atala, Anthony, Skardal, Aleks, Porada, Christopher D., Almeida-Porada, Graça
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957060/
https://ncbi.nlm.nih.gov/pubmed/33732691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.639070
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