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Immunotherapy Goes Local: The Central Role of Lymph Nodes in Driving Tumor Infiltration and Efficacy

Immune checkpoint blockade (ICB) has changed the therapeutic landscape of oncology but its impact is limited by primary or secondary resistance. ICB resistance has been related to a lack of T cells infiltrating into the tumor. Strategies to overcome this hurdle have so far focused on the tumor micro...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: van Pul, Kim M., Fransen, Marieke F., van de Ven, Rieneke, de Gruijl, Tanja D.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956978/
https://ncbi.nlm.nih.gov/pubmed/33732264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.643291
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