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Immunotherapy Goes Local: The Central Role of Lymph Nodes in Driving Tumor Infiltration and Efficacy

Immune checkpoint blockade (ICB) has changed the therapeutic landscape of oncology but its impact is limited by primary or secondary resistance. ICB resistance has been related to a lack of T cells infiltrating into the tumor. Strategies to overcome this hurdle have so far focused on the tumor micro...

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Опубликовано в: :Front Immunol
Главные авторы: van Pul, Kim M., Fransen, Marieke F., van de Ven, Rieneke, de Gruijl, Tanja D.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956978/
https://ncbi.nlm.nih.gov/pubmed/33732264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.643291
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