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Dexmedetomidine Alleviates LPS-Induced Neuronal Dysfunction by Modulating the AKT/GSK-3β/CRMP-2 Pathway in Hippocampal Neurons

OBJECTIVE: Dexmedetomidine, an α2-adrenergic receptor agonist, mitigates cognitive dysfunction in elderly patients after surgery with general anesthesia. However, the underlying mechanism by which dexmedetomidine reduces cognitive dysfunction remains to be fully elucidated. The aim of this study was...

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Detalhes bibliográficos
Publicado no:Neuropsychiatr Dis Treat
Main Authors: Zeng, Wei, Zhang, Chunyuan, Long, Qingshan, Li, Yalan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955869/
https://ncbi.nlm.nih.gov/pubmed/33727816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S297365
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