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Dexmedetomidine alleviates postoperative cognitive dysfunction by inhibiting neuron excitation in aged rats

The perioperative stress response is one of the factors leading to postoperative cognitive dysfunction (POCD). Dexmedetomidine (Dex) can reduce the stress response and hippocampus neuroapoptosis, but its mechanism of action on POCD remains unknown. This study investigated the protective effect and p...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Xiong, Bo, Shi, Qiqing, Fang, Hao
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759417/
https://ncbi.nlm.nih.gov/pubmed/27069541
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