Dexmedetomidine Alleviates LPS-Induced Neuronal Dysfunction by Modulating the AKT/GSK-3β/CRMP-2 Pathway in Hippocampal Neurons

OBJECTIVE: Dexmedetomidine, an α2-adrenergic receptor agonist, mitigates cognitive dysfunction in elderly patients after surgery with general anesthesia. However, the underlying mechanism by which dexmedetomidine reduces cognitive dysfunction remains to be fully elucidated. The aim of this study was...

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Publicat a:Neuropsychiatr Dis Treat
Autors principals: Zeng, Wei, Zhang, Chunyuan, Long, Qingshan, Li, Yalan
Format: Artigo
Idioma:Inglês
Publicat: Dove 2021
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955869/
https://ncbi.nlm.nih.gov/pubmed/33727816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S297365
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