Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Benfotiamine in Healthy Subjects

PURPOSE: Safety, tolerability and pharmacokinetics of single and multiple ascending doses (SADs/MADs) of benfotiamine were assessed after oral administration in two randomized, double-blind, placebo-controlled, phase I trials. METHODS: Healthy subjects were sequentially enrolled into one of five SAD...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Sheng, Lei, Cao, Wei, Lin, Pingping, Chen, Weili, Xu, Hongrong, Zhong, Chunjiu, Yuan, Fei, Chen, Hanjing, Li, Hui, Liu, Chao, Yang, Mengjie, Li, Xuening
Format: Artigo
Idioma:Inglês
Publicat: Dove 2021
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955752/
https://ncbi.nlm.nih.gov/pubmed/33727798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S296197
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