Laddar...
Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1
Rac1 is a major regulator of actin dynamics, with GTP-bound Rac1 promoting actin assembly via the Scar/WAVE complex. CYRI competes with Scar/WAVE for interaction with Rac1 in a feedback loop regulating actin dynamics. Here, we reveal the nature of the CYRI-Rac1 interaction, through crystal structure...
Sparad:
| I publikationen: | Structure |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cell Press
2021
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7955166/ https://ncbi.nlm.nih.gov/pubmed/33217330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.11.003 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|