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A deep learning method for HLA imputation and trans-ethnic MHC fine-mapping of type 1 diabetes
Conventional human leukocyte antigen (HLA) imputation methods drop their performance for infrequent alleles, which is one of the factors that reduce the reliability of trans-ethnic major histocompatibility complex (MHC) fine-mapping due to inter-ethnic heterogeneity in allele frequency spectra. We d...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7955122/ https://ncbi.nlm.nih.gov/pubmed/33712626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21975-x |
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