Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity

We analyzed genome-wide association studies (GWASs), including data from 71,638 individuals from four ancestries, for estimated glomerular filtration rate (eGFR), a measure of kidney function used to define chronic kidney disease (CKD). We identified 20 loci attaining genome-wide-significant evidenc...

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Publicado en:Am J Hum Genet
Autores principales: Mahajan, Anubha, Rodan, Aylin R., Le, Thu H., Gaulton, Kyle J., Haessler, Jeffrey, Stilp, Adrienne M., Kamatani, Yoichiro, Zhu, Gu, Sofer, Tamar, Puri, Sanjana, Schellinger, Jeffrey N., Chu, Pei-Lun, Cechova, Sylvia, van Zuydam, Natalie, Arnlov, Johan, Flessner, Michael F., Giedraitis, Vilmantas, Heath, Andrew C., Kubo, Michiaki, Larsson, Anders, Lindgren, Cecilia M., Madden, Pamela A.F., Montgomery, Grant W., Papanicolaou, George J., Reiner, Alex P., Sundström, Johan, Thornton, Timothy A., Lind, Lars, Ingelsson, Erik, Cai, Jianwen, Martin, Nicholas G., Kooperberg, Charles, Matsuda, Koichi, Whitfield, John B., Okada, Yukinori, Laurie, Cathy C., Morris, Andrew P., Franceschini, Nora
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011075/
https://ncbi.nlm.nih.gov/pubmed/27588450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.07.012
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