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Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain

We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type, on three newly constructed and seven previously reported mutant strains disabled in different genes require...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Iorio, Marianna, Davatgarbenam, Sahar, Serina, Stefania, Criscenzo, Paolo, Zdouc, Mitja M., Simone, Matteo, Maffioli, Sonia I., Ebright, Richard H., Donadio, Stefano, Sosio, Margherita
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955054/
https://ncbi.nlm.nih.gov/pubmed/33712632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84833-2
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