Llwytho...

Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside analog inhibitor of bacterial RNA polymerase

Pseudouridimycin (PUM) is a novel pseudouridine-containing peptidyl-nucleoside antibiotic that inhibits bacterial RNA polymerase (RNAP) through a binding site and mechanism different from those of clinically approved RNAP inhibitors of the rifamycin and lipiarmycin (fidaxomicin) classes. PUM was dis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Ind Microbiol Biotechnol
Prif Awduron: Maffioli, Sonia I., Sosio, Margherita, Ebright, Richard H., Donadio, Stefano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405294/
https://ncbi.nlm.nih.gov/pubmed/30465105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-018-2109-2
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