Wird geladen...
Multi-stage adaptive enrichment trial design with subgroup estimation
We consider the problem of estimating the best subgroup and testing for treatment effect in a clinical trial. We define the best subgroup as the subgroup that maximizes a utility function that reflects the trade-off between the subgroup size and the treatment effect. For moderate effect sizes and sa...
Gespeichert in:
| Veröffentlicht in: | J Biopharm Stat |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954857/ https://ncbi.nlm.nih.gov/pubmed/33073685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2020.1832109 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|