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A computer-guided design tool to increase the efficiency of cellular conversions

Human cell conversion technology has become an important tool for devising new cell transplantation therapies, generating disease models and testing gene therapies. However, while transcription factor over-expression-based methods have shown great promise in generating cell types in vitro, they ofte...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jung, Sascha, Appleton, Evan, Ali, Muhammad, Church, George M., del Sol, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954801/
https://ncbi.nlm.nih.gov/pubmed/33712564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21801-4
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