An abundant biliary metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides

Omega-3 fatty acids from fish oil reduce triglyceride levels in mammals, yet the mechanisms underlying this effect have not been fully clarified, despite the clinical use of omega-3 ethyl esters to treat severe hypertriglyceridemia and reduce cardiovascular disease risk in humans. Here, we identifie...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Grevengoed, Trisha J., Trammell, Samuel A.J., Svenningsen, Jens S., Makarov, Mikhail V., Nielsen, Thomas Svava, Jacobsen, Jens Christian Brings, Treebak, Jonas T., Calder, Philip C., Migaud, Marie E., Cravatt, Benjamin F., Gillum, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954602/
https://ncbi.nlm.nih.gov/pubmed/33507883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143861
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