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Methyl Jasmonate Cytotoxicity and Chemosensitization of T Cell Lymphoma In Vitro Is Facilitated by HK 2, HIF-1α, and Hsp70: Implication of Altered Regulation of Cell Survival, pH Homeostasis, Mitochondrial Functions

Methyl jasmonate (MJ) displays antineoplastic potential against numerous neoplastic cells. However, several mechanistic aspects of its antineoplastic action against malignancies of T cell origin remain elusive. The present investigation reports the novel targets of MJ and mechanistic pathways of MJ-...

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Publicado en:Front Pharmacol
Main Authors: Goel, Yugal, Yadav, Saveg, Pandey, Shrish Kumar, Temre, Mithlesh Kumar, Singh, Vinay Kumar, Kumar, Ajay, Singh, Sukh Mahendra
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954117/
https://ncbi.nlm.nih.gov/pubmed/33716751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.628329
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