[(18)F]-FDHT PET/CT as a tool for imaging androgen receptor expression in high-grade glioma

BACKGROUND: G lioblastoma (GBM) is associated with poor overall survival. Recently, we showed that androgen receptor (AR) protein is overexpressed in 56% of GBM specimens and AR antagonists induced dose-dependent death in several GBM cell lines and significantly reduced tumor growth and prolonged th...

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Dades bibliogràfiques
Publicat a:Neurooncol Adv
Autors principals: Orevi, Marina, Shamni, Ofer, Zalcman, Nomi, Chicheportiche, Alexandre, Mordechai, Anat, Moscovici, Samuel, Shoshan, Yigal, Shahar, Tal, Charbit, Hanna, Gutreiman, Mijal, Paldor, Iddo, Mishani, Eyal, Lossos, Alexander, Lavon, Iris
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Clinical Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954111/
https://ncbi.nlm.nih.gov/pubmed/33738450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab019
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