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ANGI-09. CIRCULATING MIR-10B AND MIR-21 IN PATIENTS WITH GBM TREATED WITH BEVACIZUMAB ARE SECRETED TO THE CIRCULATION BY PROTEINS AND THEIR HIGH QUANTIFICATION IS PROBABLY THE RESULT OF DRUG-INDUCED TUMOR HYPOXIA

Bevacizumab is a one of the salvage therapy to patients with recurrent GBM. Antiangiogenic treatment such bevacizumab reduce blood supply and consequently increase hypoxia in the tumor microenvironment. We previously demonstrated that miR-10b and miR-21 are highly quantified in the circulation follo...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Charbit, Hanna, Mordechai, Anat, Lossos, Alexander, Lavon, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217044/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.110
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