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Catalytic Asymmetric Synthesis of Unprotected β(2)-Amino Acids

[Image: see text] We report here a scalable, catalytic one-pot approach to enantiopure and unmodified β(2)-amino acids. A newly developed confined imidodiphosphorimidate (IDPi) catalyzes a broadly applicable reaction of diverse bis-silyl ketene acetals with a silylated aminomethyl ether, followed by...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Zhu, Chendan, Mandrelli, Francesca, Zhou, Hui, Maji, Rajat, List, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953379/
https://ncbi.nlm.nih.gov/pubmed/33645969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c00249
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