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Asymmetric synthesis of syn-propargylamines and unsaturated β-amino acids under Brønsted base catalysis

Propargylamines are important intermediates for the synthesis of polyfunctional amino derivatives and natural products and biologically active compounds. The classic method of synthesizing chiral propargylamines involves the asymmetric alkynylation of imines. Here, we report a significant advance in...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Yingcheng, Mo, Mingjie, Zhu, Kongxi, Zheng, Chao, Zhang, Hongbin, Wang, Wei, Shao, Zhihui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600747/
https://ncbi.nlm.nih.gov/pubmed/26423837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9544
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