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Asymmetric synthesis of syn-propargylamines and unsaturated β-amino acids under Brønsted base catalysis

Propargylamines are important intermediates for the synthesis of polyfunctional amino derivatives and natural products and biologically active compounds. The classic method of synthesizing chiral propargylamines involves the asymmetric alkynylation of imines. Here, we report a significant advance in...

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Vydáno v:Nat Commun
Hlavní autoři: Wang, Yingcheng, Mo, Mingjie, Zhu, Kongxi, Zheng, Chao, Zhang, Hongbin, Wang, Wei, Shao, Zhihui
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600747/
https://ncbi.nlm.nih.gov/pubmed/26423837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9544
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