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Asymmetric synthesis of syn-propargylamines and unsaturated β-amino acids under Brønsted base catalysis

Propargylamines are important intermediates for the synthesis of polyfunctional amino derivatives and natural products and biologically active compounds. The classic method of synthesizing chiral propargylamines involves the asymmetric alkynylation of imines. Here, we report a significant advance in...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Wang, Yingcheng, Mo, Mingjie, Zhu, Kongxi, Zheng, Chao, Zhang, Hongbin, Wang, Wei, Shao, Zhihui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600747/
https://ncbi.nlm.nih.gov/pubmed/26423837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9544
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