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An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity

Epithelia are continuously self-renewed, but how epithelial integrity is maintained during the morphological changes that cells undergo in mitosis is not well understood. Here, we show that as epithelial cells round up when they enter mitosis, they exert tensile forces on neighboring cells. We find...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Monster, Jooske L., Donker, Lisa, Vliem, Marjolein J., Win, Zaw, Matthews, Helen K., Cheah, Joleen S., Yamada, Soichiro, de Rooij, Johan, Baum, Buzz, Gloerich, Martijn
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953256/
https://ncbi.nlm.nih.gov/pubmed/33688935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202001042
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