Adherens junction remodelling during mitotic rounding of pseudostratified epithelial cells

Epithelial cells undergo cortical rounding at the onset of mitosis to enable spindle orientation in the plane of the epithelium. In cuboidal epithelia in culture, the adherens junction protein E‐cadherin recruits Pins/LGN/GPSM2 and Mud/NuMA to orient the mitotic spindle. In the pseudostratified colu...

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Udgivet i:EMBO Rep
Main Authors: Aguilar‐Aragon, Mario, Bonello, Teresa T, Bell, Graham P, Fletcher, Georgina C, Thompson, Barry J
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132200/
https://ncbi.nlm.nih.gov/pubmed/32030856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949700
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