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Enteric reabsorption processes and their impact on drug pharmacokinetics

Enteric reabsorption occurs when a drug is secreted into the intestinal lumen and reabsorbed into the systemic circulation. This distribution process is evidenced by multiple peaks in pharmacokinetic profiles. Commonly, hepatobiliary drug secretion is assumed to be the underlying mechanism (enterohe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ibarra, Manuel, Trocóniz, Iñaki F., Fagiolino, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952424/
https://ncbi.nlm.nih.gov/pubmed/33707635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85174-w
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