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Enteric reabsorption processes and their impact on drug pharmacokinetics

Enteric reabsorption occurs when a drug is secreted into the intestinal lumen and reabsorbed into the systemic circulation. This distribution process is evidenced by multiple peaks in pharmacokinetic profiles. Commonly, hepatobiliary drug secretion is assumed to be the underlying mechanism (enterohe...

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Publicat a:Sci Rep
Autors principals: Ibarra, Manuel, Trocóniz, Iñaki F., Fagiolino, Pietro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952424/
https://ncbi.nlm.nih.gov/pubmed/33707635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85174-w
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