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Enteric reabsorption processes and their impact on drug pharmacokinetics

Enteric reabsorption occurs when a drug is secreted into the intestinal lumen and reabsorbed into the systemic circulation. This distribution process is evidenced by multiple peaks in pharmacokinetic profiles. Commonly, hepatobiliary drug secretion is assumed to be the underlying mechanism (enterohe...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Ibarra, Manuel, Trocóniz, Iñaki F., Fagiolino, Pietro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952424/
https://ncbi.nlm.nih.gov/pubmed/33707635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85174-w
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