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Enteric reabsorption processes and their impact on drug pharmacokinetics

Enteric reabsorption occurs when a drug is secreted into the intestinal lumen and reabsorbed into the systemic circulation. This distribution process is evidenced by multiple peaks in pharmacokinetic profiles. Commonly, hepatobiliary drug secretion is assumed to be the underlying mechanism (enterohe...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ibarra, Manuel, Trocóniz, Iñaki F., Fagiolino, Pietro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952424/
https://ncbi.nlm.nih.gov/pubmed/33707635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85174-w
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