Theophylline-nicotinamide pharmaceutical co-crystals generated using hot melt extrusion technology: Impact of polymeric carriers on processability

The objective of the current study was to develop theophylline (TPH) nicotinamide (NAM) pharmaceutical co-crystals using the hot melt extrusion (HME) technology and evaluate the processability of the co-crystals using different polymeric carriers. A physical mixture of 1:1 M ratio of TPH and NAM was...

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Detaylı Bibliyografya
Yayımlandı:J Drug Deliv Sci Technol
Asıl Yazarlar: Srinivasan, Priyanka, Almutairi, Mashan, Dumpa, Nagireddy, Sarabu, Sandeep, Bandari, Suresh, Zhang, Feng, Ashour, Eman, Repka, Michael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949288/
https://ncbi.nlm.nih.gov/pubmed/33717231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jddst.2020.102128
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