Processability of AquaSolve™ LG polymer by hot-melt extrusion: Effects of pressurized CO(2) on physicomechanical properties and API stability

The objective of this study was to investigate the processability of AquaSolve™ hydroxypropyl methylcellulose acetate succinate L grade (HPMCAS LG) via hot-melt extrusion and to examine the effect of pressurized carbon dioxide (P-CO(2)) on the physicomechanical properties of efavirenz (EFA)-loaded e...

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Publicat a:J Drug Deliv Sci Technol
Autors principals: Almutairi, Mashan, Almutairy, Bjad, Sarabu, Sandeep, Almotairy, Ahmed, Ashour, Eman, Bandari, Suresh, Batra, Amol, Tewari, Divya, Durig, T., Repka, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927476/
https://ncbi.nlm.nih.gov/pubmed/31871490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jddst.2019.04.029
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