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Stable amorphous solid dispersions of fenofibrate using hot melt extrusion technology: Effect of formulation and process parameters for a low glass transition temperature drug

Development of stable amorphous solid dispersions (ASDs) for a low glass transition temperature (Tg) drug is a challenging task. The physico-chemical properties of the drug and excipients play a critical role in developing stable ASDs. In this study, ASDs of poorly soluble fenofibrate, a drug with a...

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Detalhes bibliográficos
Publicado no:J Drug Deliv Sci Technol
Main Authors: Kallakunta, Venkata Raman, Sarabu, Sandeep, Bandari, Suresh, Batra, Amol, Bi, Vivian, Durig, Thomas, Repka, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469943/
https://ncbi.nlm.nih.gov/pubmed/32905375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jddst.2019.101395
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