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Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer

Castration resistant prostate cancer (CRPC) continues to be androgen receptor (AR) driven. Inhibition of AR signaling in CRPC could be advanced using state-of-the-art biophysical and biochemical techniques. Structural characterization of AR and its complexes by cryo-electron microscopy would advance...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Asangani, Irfan, Blair, Ian A., Van Duyne, Gregory, Hilser, Vincent J., Moiseenkova-Bell, Vera, Plymate, Stephen, Sprenger, Cynthia, Wand, A. Joshua, Penning, Trevor M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949100/
https://ncbi.nlm.nih.gov/pubmed/33384381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.012411
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