Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer

Castration resistant prostate cancer (CRPC) continues to be androgen receptor (AR) driven. Inhibition of AR signaling in CRPC could be advanced using state-of-the-art biophysical and biochemical techniques. Structural characterization of AR and its complexes by cryo-electron microscopy would advance...

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Vydáno v:J Biol Chem
Hlavní autoři: Asangani, Irfan, Blair, Ian A., Van Duyne, Gregory, Hilser, Vincent J., Moiseenkova-Bell, Vera, Plymate, Stephen, Sprenger, Cynthia, Wand, A. Joshua, Penning, Trevor M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
JBC Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949100/
https://ncbi.nlm.nih.gov/pubmed/33384381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.012411
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