Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer

Castration resistant prostate cancer (CRPC) continues to be androgen receptor (AR) driven. Inhibition of AR signaling in CRPC could be advanced using state-of-the-art biophysical and biochemical techniques. Structural characterization of AR and its complexes by cryo-electron microscopy would advance...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Asangani, Irfan, Blair, Ian A., Van Duyne, Gregory, Hilser, Vincent J., Moiseenkova-Bell, Vera, Plymate, Stephen, Sprenger, Cynthia, Wand, A. Joshua, Penning, Trevor M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
JBC Reviews
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949100/
https://ncbi.nlm.nih.gov/pubmed/33384381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.012411
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