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Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons

Aggregation of α-synuclein (αS) leads to the hallmark neuropathology of Parkinson’s disease (PD) and related synucleinopathies. αS has been described to exist in both cytosolic and membrane-associated forms, the relative abundance of which has remained unsettled. To study αS under the most relevant...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Ramalingam, Nagendran, Dettmer, Ulf
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949061/
https://ncbi.nlm.nih.gov/pubmed/33428933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100271
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