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Subcellular localization of alpha-synuclein aggregates and their interaction with membranes

For more than a decade numerous evidence has been reported on the mechanisms of toxicity of α-synuclein (αS) oligomers and aggregates in α-synucleinopathies. These species were thought to form freely in the cytoplasm but recent reports of αS multimer conformations when bound to synaptic vesicles in...

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Bibliographic Details
Published in:Neural Regen Res
Main Authors: Miraglia, Fabiana, Ricci, Alessio, Rota, Lucia, Colla, Emanuela
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065224/
https://ncbi.nlm.nih.gov/pubmed/30028312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.235013
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