The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-stress–regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and non-neuronal damage. Although initially characterized...

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發表在:J Biol Chem
Main Authors: Eesmaa, Ave, Yu, Li-Ying, Göös, Helka, Nõges, Kristofer, Kovaleva, Vera, Hellman, Maarit, Zimmermann, Richard, Jung, Martin, Permi, Perttu, Varjosalo, Markku, Lindholm, Päivi, Saarma, Mart
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2021
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949057/
https://ncbi.nlm.nih.gov/pubmed/33460650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100295
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