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Biophysical characterization of the ETV6 PNT domain polymerization interfaces
ETV6 is an E26 transformation specific family transcriptional repressor that self-associates by its PNT domain to facilitate cooperative DNA binding. Chromosomal translocations frequently generate constitutively active oncoproteins with the ETV6 PNT domain fused to the kinase domain of one of many p...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7949025/ https://ncbi.nlm.nih.gov/pubmed/33450226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100284 |
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