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Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation
Multinucleated giant cells are formed by the fusion of macrophages and are a characteristic feature in numerous pathophysiological conditions including the foreign body response (FBR). Foreign body giant cells (FBGCs) are inflammatory and destructive multinucleated macrophages and may cause damage a...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948992/ https://ncbi.nlm.nih.gov/pubmed/33262217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014597 |
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