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αα-Hub domains and intrinsically disordered proteins: A decisive combo

Hub proteins are central nodes in protein–protein interaction networks with critical importance to all living organisms. Recently, a new group of folded hub domains, the αα-hubs, was defined based on a shared αα-hairpin supersecondary structural foundation. The members PAH, RST, TAFH, NCBD, and HHD...

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Foilsithe in:J Biol Chem
Main Authors: Bugge, Katrine, Staby, Lasse, Salladini, Edoardo, Falbe-Hansen, Rasmus G., Kragelund, Birthe B., Skriver, Karen
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948954/
https://ncbi.nlm.nih.gov/pubmed/33361159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.012928
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