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Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stress
The ion channels Piezo1 and TRPV4 have both, independently, been implicated in high venous pressure– and fluid shear stress–induced vascular hyperpermeability in endothelial cells. However, the mechanism by which Piezo1 and TRPV4 channels execute the same function is poorly understood. Here we demon...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948745/ https://ncbi.nlm.nih.gov/pubmed/33298523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015059 |
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