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The STAT3 inhibitor Stattic acts independently of STAT3 to decrease histone acetylation and modulate gene expression

Signal transducer and activator of transcription 3 (STAT3) is an important transcription factor involved in many physiological functions including embryonic development and immune responses and is often activated under pathological conditions such as cancer. Strategies to inactivate STAT3 are being...

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Vydáno v:J Biol Chem
Hlavní autoři: Poria, Dipak K., Sheshadri, Namratha, Balamurugan, Kuppusamy, Sharan, Shikha, Sterneck, Esta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948742/
https://ncbi.nlm.nih.gov/pubmed/33839684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.016645
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