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An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14

Astrocytes can support neuronal survival through a range of secreted signals that protect against neurotoxicity, oxidative stress, and apoptotic cascades. Thus, analyzing the effects of the astrocyte secretome may provide valuable insight into these neuroprotective mechanisms. Previously, we charact...

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Pubblicato in:J Biol Chem
Autori principali: Alqawlaq, Samih, Livne-Bar, Izhar, Williams, Declan, D'Ercole, Joseph, Leung, Sara W., Chan, Darren, Tuccitto, Alessandra, Datti, Alessandro, Wrana, Jeffrey L., Corbett, Anita H., Schmitt-Ulms, Gerold, Sivak, Jeremy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948738/
https://ncbi.nlm.nih.gov/pubmed/33234594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015389
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