An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14

Astrocytes can support neuronal survival through a range of secreted signals that protect against neurotoxicity, oxidative stress, and apoptotic cascades. Thus, analyzing the effects of the astrocyte secretome may provide valuable insight into these neuroprotective mechanisms. Previously, we charact...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Alqawlaq, Samih, Livne-Bar, Izhar, Williams, Declan, D'Ercole, Joseph, Leung, Sara W., Chan, Darren, Tuccitto, Alessandra, Datti, Alessandro, Wrana, Jeffrey L., Corbett, Anita H., Schmitt-Ulms, Gerold, Sivak, Jeremy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948738/
https://ncbi.nlm.nih.gov/pubmed/33234594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015389
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