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MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway

The Hippo pathway is an evolutionarily conserved signaling pathway that controls organ size in animals via the regulation of cell proliferation and apoptosis. It consists of a kinase cascade, in which MST1/2 and MAP4Ks phosphorylate and activate LATS1/2, which in turn phosphorylate and inhibit YAP/T...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Lu, Jinqiu, Hu, Zonghao, Deng, Yujie, Wu, Qingzhe, Wu, Ming, Song, Hai
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948509/
https://ncbi.nlm.nih.gov/pubmed/33571521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100400
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