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MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway
The Hippo pathway is an evolutionarily conserved signaling pathway that controls organ size in animals via the regulation of cell proliferation and apoptosis. It consists of a kinase cascade, in which MST1/2 and MAP4Ks phosphorylate and activate LATS1/2, which in turn phosphorylate and inhibit YAP/T...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948509/ https://ncbi.nlm.nih.gov/pubmed/33571521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100400 |
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