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The Spectrin cytoskeleton regulates the Hippo signalling pathway

The Spectrin cytoskeleton is known to be polarised in epithelial cells, yet its role remains poorly understood. Here, we show that the Spectrin cytoskeleton controls Hippo signalling. In the developing Drosophila wing and eye, loss of apical Spectrins (alpha/beta-heavy dimers) produces tissue overgr...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Fletcher, Georgina C, Elbediwy, Ahmed, Khanal, Ichha, Ribeiro, Paulo S, Tapon, Nic, Thompson, Barry J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388601/
https://ncbi.nlm.nih.gov/pubmed/25712476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489642
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