The Hippo pathway integrates PI3K–Akt signals with mechanical and polarity cues to control tissue growth

The Hippo signalling pathway restricts cell proliferation in animal tissues by inhibiting Yes-associated protein (YAP or YAP1) and Transcriptional Activator with a PDZ domain (TAZ or WW-domain–containing transcriptional activator [WWTR1]), coactivators of the Scalloped (Sd or TEAD) DNA-binding trans...

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Udgivet i:PLoS Biol
Main Authors: Borreguero-Muñoz, Nerea, Fletcher, Georgina C., Aguilar-Aragon, Mario, Elbediwy, Ahmed, Vincent-Mistiaen, Zoé I., Thompson, Barry J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814241/
https://ncbi.nlm.nih.gov/pubmed/31613895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000509
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