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The Spectrin cytoskeleton regulates the Hippo signalling pathway

The Spectrin cytoskeleton is known to be polarised in epithelial cells, yet its role remains poorly understood. Here, we show that the Spectrin cytoskeleton controls Hippo signalling. In the developing Drosophila wing and eye, loss of apical Spectrins (alpha/beta-heavy dimers) produces tissue overgr...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Fletcher, Georgina C, Elbediwy, Ahmed, Khanal, Ichha, Ribeiro, Paulo S, Tapon, Nic, Thompson, Barry J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388601/
https://ncbi.nlm.nih.gov/pubmed/25712476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489642
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