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Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation

Heat shock transcription factor 1 (HSF1) orchestrates cellular stress protection by activating or repressing gene transcription in response to protein misfolding, oncogenic cell proliferation, and other environmental stresses. HSF1 is tightly regulated via intramolecular repressive interactions, pos...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Burchfiel, Eileen T., Vihervaara, Anniina, Guertin, Michael J., Gomez-Pastor, Rocio, Thiele, Dennis J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948500/
https://ncbi.nlm.nih.gov/pubmed/33208463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015452
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